Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 12/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837035 | 0.87 | ADA (0.59) | ADAHDAC3HDAC1HDAC6 | |
| SCHEMBL7846603 | 0.84 | ADA (0.54) | ADAMCHR1HDAC3HDAC1HDAC6 | |
| SCHEMBL7850182 | 0.77 | ADA (0.54) | ADACNR1MCHR1 | |
| SCHEMBL7827408 | 0.77 | CNR1 (0.47) | CNR1MAPT | |
| SCHEMBL6936476 | 0.75 | ADA (1.00) | ADA | |
| SCHEMBL7836409 | 0.75 | ADA (0.58) | ADA | |
| SCHEMBL7847122 | 0.74 | ADA (0.50) | ADAMCHR1ALDH1A1MAPTHDAC3 | |
| SCHEMBL7850108 | 0.74 | ADA (0.39) | ADAALDH1A1MAPT | |
| SCHEMBL7846463 | 0.73 | ADA (0.40) | ADAALDH1A1MAPTHDAC3HDAC1 | |
| SCHEMBL7845082 | 0.73 | ADA (0.38) | ADACNR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161429-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055155-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-21 | — | — | WO | disclosed |