Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836024 | 0.91 | ALDH1A1 (0.56) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL7849307 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2466528 | 0.75 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL15218938 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL961555 | 0.70 | ALDH1A1 (0.47) | ALDH1A1POLBKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11349289 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2048930 | 0.69 | ALDH1A1 (0.57) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL8540776 | 0.68 | AMY1A (0.48) | ALDH1A1KDM4EKMT2ARAB9AMAPT | |
| SCHEMBL31463535 | 0.68 | AMY1A (0.48) | ALDH1A1KDM4EKMT2ARAB9AMAPT | |
| SCHEMBL367990 | 0.68 | MAPT (0.47) | ALDH1A1POLBKMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121358-A1 | HETEROCYCLYLAMINOMETHYLOXAZOLIDINONES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021960-A1 | HETEROCYCLYL AMINO METHYLOXA ZOLIDINONES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2000-04-20 | — | — | WO | disclosed |