Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.68 |
| ▸ | MMP3 | P08254 | 2/20 | 0.68 |
| ▸ | MMP9 | P14780 | 2/20 | 0.68 |
| ▸ | MMP8 | P22894 | 2/20 | 0.68 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.56 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 9/20 | 0.54 |
| ▸ | NMBR | P28336 | 2/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261304 | 0.82 | MMP2 (0.57) | MMP2MMP3MMP9MMP8MAPT | |
| SCHEMBL5652426 | 0.82 | TAOK1 (0.60) | MMP2MMP3MMP9MMP8TAOK1 | |
| SCHEMBL31730289 | 0.82 | TAOK1 (0.60) | MMP2MMP3MMP9MMP8TAOK1 | |
| SCHEMBL5653439 | 0.82 | TAOK1 (0.60) | MMP2MMP3MMP9MMP8TAOK1 | |
| SCHEMBL7854930 | 0.81 | POLB (0.60) | MMP2MMP3MMP9MMP8POLB | |
| SCHEMBL7846847 | 0.80 | HPGD (0.67) | MMP2MMP3MMP9MMP8MAPT | |
| SCHEMBL7675962 | 0.79 | MMP2 (0.63) | MMP2MMP9MMP8POLBKDM4E | |
| SCHEMBL14261305 | 0.78 | HPGD (0.58) | MMP2MMP3MMP9MMP8KDM4E | |
| SCHEMBL24105928 | 0.78 | MMP2 (0.48) | MMP2MMP3MMP9MMP8TAOK1 | |
| SCHEMBL9268039 | 0.77 | NMBR (0.65) | NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |