Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 15/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850931 | 0.89 | DHPS (0.69) | DHPSADORA1DHFR | |
| SCHEMBL7848869 | 0.87 | DHPS (0.49) | DHPSADORA1ADORA3ADORA2ADHFR | |
| SCHEMBL7849040 | 0.81 | DHPS (0.81) | DHPSADORA1DHFR | |
| SCHEMBL7850930 | 0.78 | DHPS (0.56) | DHPSADORA1 | |
| SCHEMBL8638012 | 0.77 | DHPS (0.39) | DHPS | |
| SCHEMBL31037808 | 0.76 | DHPS (0.81) | DHPS | |
| SCHEMBL31037833 | 0.76 | DHPS (0.79) | DHPS | |
| SCHEMBL31037810 | 0.76 | DHPS (0.79) | DHPS | |
| SCHEMBL31037829 | 0.72 | DHPS (0.86) | DHPS | |
| SCHEMBL31037827 | 0.70 | DHPS (0.86) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713875-B1 | Sulfonamides | HOFFMANN LA ROCHE (CH) | 2001-03-21 | — | — | EP | claimed |
| WO-2001049289-A1 | PHARMACEUTICAL AND VETERINARY USES OF ENDOTHELIN ANTAGONISTS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |