Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.41 |
| ▸ | CLK1 | P49759 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080309 | 0.88 | MAPT (0.36) | KMT2ANPC1RAB9ACYP1A2ALDH1A1 | |
| SCHEMBL7840491 | 0.83 | NPC1 (0.54) | KMT2ANPC1MEN1PIM1PIM2 | |
| SCHEMBL7848396 | 0.81 | MAPT (0.45) | CYP1A2PIM1PIM2ALDH1A1CYP2A6 | |
| SCHEMBL7848283 | 0.81 | MAPT (0.45) | CYP1A2PIM1PIM2ALDH1A1CYP2A6 | |
| SCHEMBL13299357 | 0.76 | NPC1 (0.37) | KMT2ANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL7848281 | 0.76 | NPC1 (0.42) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL28902601 | 0.75 | KMT2A (0.50) | KMT2ANPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL3438538 | 0.71 | NPC1 (0.64) | KMT2ANPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL3438540 | 0.71 | NPC1 (0.64) | KMT2ANPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL3438260 | 0.70 | CYP1A2 (0.50) | KMT2ANPC1RAB9ACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | claimed |
| US-5840282-A | SUNSCREEN AGENTS; BENZYLIDENE-TYPE STABILIZER | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-11-24 | — | — | US | claimed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | claimed |
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | disclosed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | disclosed |