Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.38 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848283 | 1.00 | MAPT (0.45) | MAPTHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14080309 | 0.92 | MAPT (0.36) | MAPTHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13299357 | 0.79 | NPC1 (0.37) | MAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7848281 | 0.76 | NPC1 (0.42) | MAPTHPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7840491 | 0.75 | NPC1 (0.54) | MAPTHPGDLMNAALDH1A1HTT | |
| SCHEMBL8304457 | 0.70 | PRSS1 (0.31) | F2PRSS1 | |
| SCHEMBL94584 | 0.69 | CYP1A2 (0.47) | MAPTHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4665877 | 0.69 | CYP1A2 (0.47) | MAPTHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3438541 | 0.67 | MAPT (0.59) | MAPTHPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5611750 | 0.67 | MAPT (0.59) | MAPTHPGDCYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | claimed |
| US-5840282-A | SUNSCREEN AGENTS; BENZYLIDENE-TYPE STABILIZER | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-11-24 | — | — | US | claimed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | claimed |
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | disclosed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | disclosed |