Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848942 | 0.83 | KMT2A (0.51) | NPC1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7848281 | 0.78 | NPC1 (0.42) | NPC1MAPTLMNAGAAMAPK1 | |
| SCHEMBL7848396 | 0.75 | MAPT (0.45) | MAPTLMNAGAAALDH1A1PIM1 | |
| SCHEMBL29705880 | 0.70 | NPC1 (1.00) | NPC1MAPTPLIN1LMNAGAA | |
| SCHEMBL31432748 | 0.69 | MAPT (0.59) | NPC1MAPTPLIN1LMNAGAA | |
| SCHEMBL31432760 | 0.66 | MAPT (0.88) | NPC1MAPTPLIN1LMNAGAA | |
| SCHEMBL31432701 | 0.66 | MAPT (0.88) | NPC1MAPTPLIN1LMNAGAA | |
| SCHEMBL19050165 | 0.66 | MAPT (0.88) | NPC1MAPTPLIN1LMNAGAA | |
| SCHEMBL7990683 | 0.66 | KMT2A (0.54) | NPC1MAPTPLIN1LMNAGAA | |
| SCHEMBL9377078 | 0.66 | ALDH1A1 (0.51) | NPC1MAPTLMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | claimed |
| US-5840282-A | SUNSCREEN AGENTS; BENZYLIDENE-TYPE STABILIZER | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-11-24 | — | — | US | claimed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | claimed |
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | disclosed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | disclosed |