Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAT1 | P18440 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TFEB | P19484 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840491 | 0.78 | NPC1 (0.54) | NPC1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL7848396 | 0.76 | MAPT (0.45) | ALDH1A1MAPTGAALMNAMIF | |
| SCHEMBL7848283 | 0.76 | MAPT (0.45) | ALDH1A1MAPTGAALMNAMIF | |
| SCHEMBL7848942 | 0.76 | KMT2A (0.51) | NPC1RAB9AALDH1A1MAPTEGFR | |
| SCHEMBL7839790 | 0.75 | ALDH1A1 (0.45) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL14080309 | 0.74 | MAPT (0.36) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL3438503 | 0.73 | NPC1 (0.52) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL3438502 | 0.73 | NPC1 (0.52) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL3438419 | 0.72 | EGFR (0.43) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL3438421 | 0.72 | EGFR (0.43) | NPC1RAB9AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | claimed |
| US-5840282-A | SUNSCREEN AGENTS; BENZYLIDENE-TYPE STABILIZER | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-11-24 | — | — | US | claimed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | claimed |
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | disclosed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | disclosed |