Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | UBE2M | P61081 | 2/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848872 | 0.92 | KMT2A (0.49) | CCR3KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL7848873 | 0.90 | CCR3 (0.59) | CCR3KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL7848854 | 0.84 | HDAC3 (0.57) | KMT2ASMN1; SMN2MEN1PKMLMNA | |
| SCHEMBL6802404 | 0.80 | SMN1; SMN2 (0.56) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL7855189 | 0.80 | KMT2A (0.54) | CCR3KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL7848867 | 0.75 | KMT2A (0.51) | CCR3KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL7849483 | 0.75 | HDAC3 (0.56) | KMT2ASMN1; SMN2MEN1PKMLMNA | |
| SCHEMBL7847020 | 0.73 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1PKMDRD4 | |
| Hydrochloric Acid SCHEMBL7551006 | 0.73 | LMNA (0.45) | KMT2ASMN1; SMN2MEN1PKMLMNA | |
| Hydrochloric Acid SCHEMBL8123446 | 0.73 | LMNA (0.45) | KMT2ASMN1; SMN2MEN1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |