Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848948 | 0.90 | CCR3 (0.54) | CCR3KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL7855189 | 0.89 | KMT2A (0.54) | CCR3KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL7847020 | 0.82 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1PKMDRD4 | |
| SCHEMBL7848867 | 0.82 | KMT2A (0.51) | CCR3KMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL7848872 | 0.81 | KMT2A (0.49) | CCR3KMT2ASMN1; SMN2MEN1PKM | |
| Hydrochloric Acid SCHEMBL7850655 | 0.78 | HDAC3 (0.61) | KMT2ASMN1; SMN2MEN1PKMLMNA | |
| SCHEMBL11764729 | 0.74 | ADORA3 (0.55) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL11766694 | 0.74 | ADORA3 (0.52) | KMT2AMEN1LMNAALDH1A1HTT | |
| Glyhexamide SCHEMBL185244 | 0.74 | ADORA3 (0.64) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| Glyhexamide SCHEMBL27491055 | 0.74 | ADORA3 (0.64) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |