Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 5/20 | 0.47 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.44 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | CCR4 | P51679 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855189 | 0.92 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1PKMLMNA | |
| SCHEMBL7847020 | 0.85 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1PKMLMNA | |
| SCHEMBL7848872 | 0.84 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1PKMLMNA | |
| SCHEMBL7848873 | 0.82 | CCR3 (0.59) | KMT2ASMN1; SMN2MEN1PKMLMNA | |
| SCHEMBL7848464 | 0.80 | HTR2C (0.70) | KMT2ASMN1; SMN2MEN1PKMACHE | |
| SCHEMBL6802856 | 0.75 | HTR7 (0.58) | KMT2ASMN1; SMN2ACHELMNAALDH1A1 | |
| SCHEMBL7848948 | 0.75 | CCR3 (0.54) | KMT2ASMN1; SMN2MEN1PKMLMNA | |
| Hydrochloric Acid SCHEMBL6798090 | 0.75 | HTR7 (0.57) | KMT2ASMN1; SMN2ACHELMNAALDH1A1 | |
| SCHEMBL14489818 | 0.74 | ACHE (0.72) | ACHESIGMAR1DRD4SLC6A12SLC6A13 | |
| Hydrochloric Acid SCHEMBL7850655 | 0.70 | HDAC3 (0.61) | KMT2ASMN1; SMN2MEN1PKMACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |