SCHEMBL784919

SCHEMBL784919

Cc1cc2c(c(C)c1O)OCO2

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.36
NQO2 P16083 2/20 0.36
CYP19A1 P11511 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
POLB P06746 2/20 0.34
TARBP2 Q15633 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
UGT1A1 P22309 1/20 0.33
UGT1A8 Q9HAW9 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22433011 0.84 NQO2 (0.39) CYP3A4NQO2CYP19A1POLBTARBP2
SCHEMBL12341984 0.81 NQO2 (0.42) CYP3A4NQO2CYP19A1POLBALDH1A1
SCHEMBL14284003 0.78 BCL2 (0.33) CYP3A4NQO2CYP19A1CA1CA2
SCHEMBL14284000 0.78 CYP3A4 (0.38) CYP3A4NQO2CYP19A1POLBALDH1A1
SCHEMBL6989495 0.77 LMNA (0.46) NQO2CYP19A1ALDH1A1LMNAMAPT
SCHEMBL14747985 0.77 KDM4E (0.46) POLBALDH1A1KDM4ELMNAGAA
SCHEMBL14284002 0.77 CYP3A4 (0.37) CYP3A4NQO2CYP19A1POLBTARBP2
SCHEMBL9724991 0.76 NQO2 (0.39) CYP3A4NQO2CYP19A1POLBALDH1A1
SCHEMBL9908795 0.75 CYP3A4 (0.40) CYP3A4POLBTARBP2ALDH1A1LMNA
SCHEMBL15984238 0.74 NQO2 (0.40) CYP3A4NQO2CYP19A1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
EP-1515192-B1 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH CO LTD (JP) 2015-07-15 EP disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-20130072586-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2013-03-21 US disclosed
US-8252884-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2012-08-28 US disclosed
US-20120004150-A1 Lubricant Oil Compositions POLNOX CORPORATION 2012-01-05 US disclosed
US-8008423-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2011-08-30 US disclosed
US-20100305251-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2010-12-02 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-7595074-B2 Polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2009-09-29 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed