Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | AADAT | Q8N5Z0 | 4/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | KYAT3 | Q6YP21 | 2/20 | 0.41 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835962 | 0.72 | GAA (0.43) | ACHEKDM4EPOLB | |
| SCHEMBL4070986 | 0.71 | SRC (0.42) | ACHEAADATKYAT3 | |
| Hydrochloric Acid SCHEMBL7420949 | 0.70 | SRC (0.41) | ACHEAADATKYAT3 | |
| SCHEMBL8542873 | 0.68 | ADRA1A (0.63) | ACHEADRA1ALMNAPOLB | |
| Hydrochloric Acid SCHEMBL9432424 | 0.68 | AADAT (0.47) | AADATKYAT3KYAT1 | |
| SCHEMBL13007381 | 0.67 | ANPEP (0.40) | AADATKYAT3KYAT1 | |
| Hydrochloric Acid SCHEMBL9696131 | 0.67 | ADRA1A (0.61) | ACHEADRA1ALMNAPOLB | |
| Hydrochloric Acid SCHEMBL2841681 | 0.66 | ANPEP (0.42) | AADATKYAT3KYAT1 | |
| SCHEMBL12569201 | 0.66 | AADAT (0.39) | ACHEAADATPOLB | |
| SCHEMBL4795933 | 0.66 | AADAT (0.52) | ACHEAADATADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802922-B1 | NOVEL AMINO ACID DERIVATIVES, METHOD OF PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (DE) | 2001-09-26 | — | — | EP | disclosed |
| EP-0802922-A1 | NOVEL AMINO ACID DERIVATIVES, METHOD OF PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995023810-A1 | NOVEL AMINO ACID DERIVATIVES, METHOD OF PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1995-09-08 | — | — | WO | disclosed |