Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851383 | 0.82 | ALOX15 (0.40) | NAPRTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL393492 | 0.80 | NAPRT (0.38) | NAPRTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL7848782 | 0.80 | KMT2A (0.41) | NAPRTSMN1; SMN2KDM4ELMNAMAPK1 | |
| SCHEMBL8880585 | 0.79 | ATR (0.51) | — | |
| SCHEMBL9980898 | 0.78 | ATR (0.42) | RAB9ANPC1SMN1; SMN2HTTPOLB | |
| SCHEMBL7850043 | 0.77 | LMNA (0.41) | RAB9ANPC1SMN1; SMN2HTTPOLB | |
| SCHEMBL29036756 | 0.76 | CCR1 (0.37) | SMN1; SMN2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL7848813 | 0.76 | KDM4E (0.39) | SMN1; SMN2KDM4ETP53KMOLMNA | |
| SCHEMBL8927233 | 0.75 | L3MBTL1 (0.50) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL7850639 | 0.75 | PDE4D (0.40) | RAB9ANPC1KDM4EHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| EP-0717743-A1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-06-26 | — | — | EP | disclosed |