SCHEMBL7849702

SCHEMBL7849702

Clc1nc(-c2ccc(Br)cc2)nc(Cl)c1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
HTT P42858 1/20 0.53
KMT2A Q03164 1/20 0.53
NR1H4 Q96RI1 1/20 0.51
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
NPC1 O15118 1/20 0.50
NFKB1 P19838 1/20 0.50
RAB9A P51151 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NR1H2 P55055 4/20 0.49
NR1H3 Q13133 4/20 0.49
LMNA P02545 2/20 0.49
DGAT1 O75907 1/20 0.49
CYP1B1 Q16678 2/20 0.46
CYP1A1 P04798 1/20 0.46
CYP1A2 P05177 1/20 0.46
DHPS P49366 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31626660 0.88 MEN1 (0.61) MEN1HTTKMT2AALDH1A1MAPK1
SCHEMBL3427195 0.88 MEN1 (0.65) MEN1HTTKMT2AALDH1A1MAPK1
Methyl Alcohol SCHEMBL10711715 0.82 MEN1 (0.59) MEN1HTTKMT2AALDH1A1MAPK1
SCHEMBL31626532 0.82 MEN1 (0.50) MEN1HTTKMT2AALDH1A1NPC1
SCHEMBL2161418 0.82 ALDH1A1 (0.67) MEN1KMT2ANR1H4ALDH1A1MAPK1
SCHEMBL2627622 0.82 ALDH1A1 (0.67) MEN1KMT2ANR1H4ALDH1A1MAPK1
SCHEMBL8660654 0.81 LMNA (0.58) MEN1HTTKMT2AALDH1A1NPC1
SCHEMBL28367960 0.81 NR1H4 (0.55) MEN1HTTKMT2ANR1H4ALDH1A1
SCHEMBL21382820 0.80 ALDH1A1 (0.71) MEN1KMT2ANR1H4ALDH1A1MAPK1
SCHEMBL21384241 0.80 ALDH1A1 (0.71) MEN1KMT2ANR1H4ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025127248-A1 ORGANIC LIGHT-EMITTING COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 솔루스첨단소재 주식회사 2025-06-19 WO disclosed
US-6326327-B1 LIGANDS DEGUSSA AG (DE) 2001-12-04 US disclosed
EP-0941228-B1 PROCESS FOR PREPARING MeO-Peg-PROTECTED DIHYDROQUININE OR DIHYDROQUINIDINE DERIVATIVES, DIHYDROQUININE OR DIHYDROQUINIDINE DERIVATIVES AND THEIR USE DEGUSSA (DE) 2001-08-01 EP disclosed
US-6180551-B1 ENANTIOSELECTIVE DIHYDROXYLATION DEGUSSA AG (DE) 2001-01-30 US disclosed