Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086953 | 0.93 | KMT2A (0.35) | MEN1KMT2ATDP1GSK3BMAPT | |
| SCHEMBL6087200 | 0.81 | KMT2A (0.34) | MEN1KMT2ATDP1GSK3BMAPT | |
| SCHEMBL7851704 | 0.80 | GSK3B (0.32) | GSK3BMAPTTHRBSMN1; SMN2 | |
| SCHEMBL8204210 | 0.80 | HPGD (0.40) | MEN1KMT2A | |
| SCHEMBL6086801 | 0.78 | DRD1 (0.35) | MEN1KMT2ATDP1GSK3BMAPT | |
| SCHEMBL7846777 | 0.76 | SMN1; SMN2 (0.34) | MEN1KMT2AGSK3BMAPTTHRB | |
| SCHEMBL8336664 | 0.75 | GRIN1 (0.39) | MEN1KMT2A | |
| SCHEMBL8173986 | 0.75 | DAO (0.38) | DHODHMEN1KMT2AMAPT | |
| SCHEMBL7849809 | 0.74 | GRIN1 (0.38) | MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7851350 | 0.74 | DHODH (0.40) | DHODHMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |