Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086953 | 0.87 | KMT2A (0.35) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL7846777 | 0.85 | SMN1; SMN2 (0.34) | KMT2AMEN1MAPTSMN1; SMN2THRB | |
| SCHEMBL6086522 | 0.84 | SMN1; SMN2 (0.33) | MAPTSMN1; SMN2THRBLMNAGSK3B | |
| SCHEMBL6087839 | 0.83 | MAPT (0.32) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL7849860 | 0.81 | DHODH (0.33) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL6636874 | 0.80 | SMN1; SMN2 (0.33) | KMT2AMEN1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL7852882 | 0.80 | GSK3B (0.31) | GSK3B | |
| SCHEMBL7850530 | 0.78 | — | — | |
| SCHEMBL6088109 | 0.78 | KMT2A (0.37) | KMT2AMEN1TDP1MAPTALDH1A1 | |
| SCHEMBL6089258 | 0.77 | KMT2A (0.41) | KMT2AMEN1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |