Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851704 | 0.93 | GSK3B (0.32) | DRD1MAPTSMN1; SMN2THRBGSK3B | |
| SCHEMBL6086522 | 0.86 | SMN1; SMN2 (0.33) | MAPTSMN1; SMN2THRBGSK3BGAA | |
| SCHEMBL6086953 | 0.84 | KMT2A (0.35) | DRD1MAPTSMN1; SMN2THRBGSK3B | |
| SCHEMBL7852882 | 0.81 | GSK3B (0.31) | GSK3B | |
| SCHEMBL7849860 | 0.78 | DHODH (0.33) | MAPTSMN1; SMN2THRBGSK3BKMT2A | |
| SCHEMBL6087044 | 0.76 | SMN1; SMN2 (0.37) | DRD1MAPTSMN1; SMN2THRBGAA | |
| SCHEMBL6086864 | 0.76 | HPGD (0.44) | MAPTGAANPSR1ALDH1A1HSD17B10 | |
| SCHEMBL6087042 | 0.75 | SMN1; SMN2 (0.36) | DRD1MAPTSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6085479 | 0.74 | MTNR1A (0.37) | MAPTSMN1; SMN2GAANPSR1ALDH1A1 | |
| SCHEMBL6086483 | 0.73 | MTNR1A (0.50) | ALDH1A1HSD17B10KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |