Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | GAA | P10253 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087200 | 0.85 | KMT2A (0.34) | SMN1; SMN2LMNAMAPTTHRBALDH1A1 | |
| SCHEMBL6086522 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2LMNAMAPTTHRBALDH1A1 | |
| SCHEMBL6086953 | 0.78 | KMT2A (0.35) | SMN1; SMN2MAPTTHRBALDH1A1GAA | |
| SCHEMBL6087839 | 0.78 | MAPT (0.32) | SMN1; SMN2LMNAMAPTTHRBALDH1A1 | |
| SCHEMBL7846575 | 0.77 | HPD (0.41) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7849860 | 0.76 | DHODH (0.33) | SMN1; SMN2MAPTTHRBKMT2AGSK3B | |
| SCHEMBL7848710 | 0.76 | MTNR1A (0.37) | SMN1; SMN2LMNAMAPTALDH1A1GAA | |
| SCHEMBL7847168 | 0.76 | MTNR1A (0.49) | MAPTTHRBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7846719 | 0.74 | TYMS (0.41) | ALDH1A1KDM4ECHRM4CHRM3 | |
| SCHEMBL7847828 | 0.74 | MEN1 (0.33) | SMN1; SMN2MAPTALDH1A1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |