Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075028 | 0.86 | CYP3A4 (0.46) | FASNCYP3A4HPGDLMNATP53 | |
| SCHEMBL784922 | 0.85 | CYP3A4 (0.44) | FASNCYP3A4HPGDLMNATP53 | |
| SCHEMBL2741241 | 0.85 | CYP3A4 (0.44) | FASNCYP3A4HPGDLMNATP53 | |
| SCHEMBL14788891 | 0.84 | TP53 (0.47) | CYP3A4HPGDLMNATP53ALOX15 | |
| SCHEMBL25404759 | 0.77 | CYP3A4 (0.52) | FASNCYP3A4HPGDLMNATP53 | |
| SCHEMBL18747579 | 0.77 | ACHE (0.40) | CYP3A4HPGDLMNATP53ALOX15 | |
| SCHEMBL5518244 | 0.77 | CYP3A4 (0.52) | FASNCYP3A4HPGDLMNATP53 | |
| SCHEMBL1144365 | 0.76 | CYP3A4 (0.52) | CYP3A4HPGDLMNATP53ALOX15 | |
| SCHEMBL6234048 | 0.73 | CYP3A4 (0.47) | CYP3A4HPGDLMNATP53ALOX15 | |
| SCHEMBL785142 | 0.73 | CYP3A4 (0.40) | CYP3A4HPGDLMNATP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9523060-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |
| US-20150159109-A1 | Lubricant Oil Compositions | POLNOX CORPORATION | 2015-06-11 | — | — | US | disclosed |
| US-8927472-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140011901-A1 | Stabilized Polyolefin Compositions | POLNOX CORPORATION (US) | 2014-01-09 | — | — | US | disclosed |
| US-8481670-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| US-20130130955-A1 | LUBRICANT OIL COMPOSITIONS | POLNOX CORPORATION (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130072586-A1 | Stabilized Polyolefin Compositions | POLNOX CORPORATION (US) | 2013-03-21 | — | — | US | disclosed |
| US-8252884-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2012-08-28 | — | — | US | disclosed |
| US-20120071596-A1 | STABILIZED POLYOLEFIN COMPOSITIONS | POLNOX CORPORATION | 2012-03-22 | — | — | US | disclosed |
| US-8008423-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2011-08-30 | — | — | US | disclosed |
| US-20100305251-A1 | STABILIZED POLYOLEFIN COMPOSITIONS | POLNOX CORPORATION | 2010-12-02 | — | — | US | disclosed |