SCHEMBL784922

SCHEMBL784922

COc1cc(O)c(C)c(O)c1C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.44
LMNA P02545 2/20 0.44
TP53 P04637 2/20 0.44
HPGD P15428 2/20 0.44
ALOX15 P16050 2/20 0.44
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
FASN P49327 1/20 0.38
ALOX5 P09917 5/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
ALOX12 P18054 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HTT P42858 1/20 0.36
MAOB P27338 1/20 0.35
PTGS2 P35354 1/20 0.35
HMGCR P04035 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL785019 0.85 FASN (0.45) CYP3A4LMNATP53HPGDALOX15
SCHEMBL14788891 0.84 TP53 (0.47) CYP3A4LMNATP53HPGDALOX15
SCHEMBL4075028 0.78 CYP3A4 (0.46) CYP3A4LMNATP53HPGDALOX15
SCHEMBL18747579 0.77 ACHE (0.40) CYP3A4LMNATP53HPGDALOX15
SCHEMBL25404759 0.77 CYP3A4 (0.52) CYP3A4LMNATP53HPGDALOX15
SCHEMBL2741241 0.77 CYP3A4 (0.44) CYP3A4LMNATP53HPGDALOX15
SCHEMBL785142 0.77 CYP3A4 (0.40) CYP3A4LMNATP53HPGDALOX15
SCHEMBL785005 0.76 TP53 (0.52) CYP3A4LMNATP53HPGDALOX15
SCHEMBL5587534 0.74 ALOX15 (0.55) CYP3A4LMNATP53HPGDALOX15
SCHEMBL27851718 0.74 SMN1; SMN2 (0.52) CYP3A4LMNATP53HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-8252884-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2012-08-28 US disclosed
US-20120071596-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2012-03-22 US disclosed
US-20120004150-A1 Lubricant Oil Compositions POLNOX CORPORATION 2012-01-05 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-7678877-B2 Process for the synthesis of polyalkylphenol antioxidants POLNOX CORPORATION (US) 2010-03-16 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed