Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | PRKACG | P22612 | 2/20 | 0.41 |
| ▸ | PRKACB | P22694 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PRKCB | P05771 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10776657 | 0.71 | BRD4 (0.43) | PIM1PRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8520286 | 0.71 | HSP90AA1 (0.54) | SIRT2SIRT1MEN1MAPTKMT2A | |
| SCHEMBL27881711 | 0.71 | KDM4E (0.43) | ATMMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL17861173 | 0.71 | ATM (0.45) | SIRT2SIRT1GPR84CYP2A6IMPDH2 | |
| SCHEMBL856333 | 0.68 | TLR9 (0.52) | SIRT2SIRT1CCNE2CDK4PRKACA | |
| SCHEMBL19924468 | 0.68 | CA12 (0.41) | SIRT2SIRT1CCNE2CDK4PRKACA | |
| SCHEMBL28167164 | 0.68 | SIRT2 (0.41) | SIRT2SIRT1CCNE2CDK4PRKACA | |
| SCHEMBL3044022 | 0.67 | SMN1; SMN2 (0.43) | SIRT2SIRT1CCNE2CDK4PRKACA | |
| SCHEMBL30688235 | 0.67 | SMN1; SMN2 (0.43) | SIRT2SIRT1CCNE2CDK4PRKACA | |
| SCHEMBL19444481 | 0.67 | SIRT2 (0.40) | SIRT2SIRT1CCNE2CDK4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266310-B1 | Chromogenic phthalides | CIBA SC HOLDING AG (CH) | 2001-12-05 | — | — | EP | disclosed |