Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15348811 | 0.78 | GAA (0.64) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL994563 | 0.77 | RAB9A (0.55) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL996720 | 0.77 | L3MBTL1 (0.55) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6536229 | 0.73 | CSNK2A2 (0.55) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6256084 | 0.73 | RAB9A (0.52) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2903601 | 0.73 | RAB9A (0.51) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2906397 | 0.73 | RAB9A (0.51) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6675218 | 0.73 | TSHR (0.56) | L3MBTL1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9634152 | 0.73 | L3MBTL1 (0.50) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6578768 | 0.72 | RAB9A (0.51) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121358-A1 | HETEROCYCLYLAMINOMETHYLOXAZOLIDINONES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021960-A1 | HETEROCYCLYL AMINO METHYLOXA ZOLIDINONES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2000-04-20 | — | — | WO | disclosed |