SCHEMBL996720

SCHEMBL996720

CCCCOC(=O)Nc1ncncn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.55
RAB9A P51151 9/20 0.52
NPC1 O15118 7/20 0.52
SMN1; SMN2 Q16637 7/20 0.52
CASP1 P29466 1/20 0.52
GAA P10253 1/20 0.49
ALDH1A1 P00352 6/20 0.49
HPGD P15428 5/20 0.49
KDM4E B2RXH2 2/20 0.49
MAPK1 P28482 2/20 0.49
MAPT P10636 1/20 0.49
MCL1 Q07820 1/20 0.49
CYP1A2 P05177 3/20 0.47
CYP2C19 P33261 3/20 0.47
LMNA P02545 2/20 0.47
CSNK2A2 P19784 1/20 0.46
CSNK2A1 P68400 1/20 0.46
NFKB1 P19838 1/20 0.46
STAT1 P42224 1/20 0.46
NFKB2 Q00653 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634152 0.95 L3MBTL1 (0.50) L3MBTL1RAB9ANPC1SMN1; SMN2CASP1
SCHEMBL4422292 0.86 RAB9A (0.41) L3MBTL1RAB9ANPC1SMN1; SMN2CASP1
SCHEMBL15348811 0.85 GAA (0.64) L3MBTL1RAB9ANPC1SMN1; SMN2CASP1
SCHEMBL6256084 0.83 RAB9A (0.52) L3MBTL1RAB9ANPC1SMN1; SMN2CASP1
SCHEMBL6657424 0.83 ALDH1A1 (0.46) RAB9ANPC1SMN1; SMN2ALDH1A1HPGD
SCHEMBL6270005 0.82 RAB9A (0.51) L3MBTL1RAB9ANPC1SMN1; SMN2CASP1
SCHEMBL6578768 0.82 RAB9A (0.51) L3MBTL1RAB9ANPC1SMN1; SMN2CASP1
SCHEMBL994563 0.81 RAB9A (0.55) L3MBTL1RAB9ANPC1SMN1; SMN2CASP1
SCHEMBL6536229 0.80 CSNK2A2 (0.55) L3MBTL1RAB9ANPC1SMN1; SMN2CASP1
SCHEMBL7850474 0.77 L3MBTL1 (0.51) L3MBTL1RAB9ANPC1SMN1; SMN2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7188194-A None JP disclosed
EP-2456799-A1 WATER-BORNE BINDERS FOR PRIMER-SURFACER COATING COMPOSITIONS Cytec Austria GmbH (AT) 2012-05-30 EP disclosed
WO-2011009882-A1 WATER-BORNE BINDERS FOR PRIMER-SURFACER COATING COMPOSITIONS CYTEC AUSTRIA GMBH (AT) 2011-01-27 WO disclosed
WO-2007009581-A1 WATER REDUCIBLE BINDERS FOR CATHODIC ELECTRODEPOSITION COATING COMPOSITIONS CYTEC SURFACE SPECIALTIES AUSTRIA GMBH (AT) 2007-01-25 WO disclosed
EP-1743925-A1 Water reducible binders for cathodic electrodeposition coating compositions Cytec Surface Specialties Austria GmbH (AT) 2007-01-17 EP disclosed
EP-1575927-A2 METHOD FOR THE PRODUCTION OF ALKOXYCARBONYLAMINO TRIAZINES BASF AKTIENGESELLSCHAFT (DE) 2005-09-21 EP disclosed
EP-1440065-A1 METHOD FOR PREPARING ALKOXYCARBONYLAMINO-TRIAZINES BASF AKTIENGESELLSCHAFT (DE) 2004-07-28 EP disclosed
WO-2004054990-A2 METHOD FOR THE PRODUCTION OF ALKOXYCARBONYLAMINO TRIAZINES BASF AKTIENGESELLSCHAFT (DE) 2004-07-01 WO disclosed
WO-2003035628-A1 METHOD FOR PREPARING ALKOXYCARBONYLAMINO-TRIAZINES BASF AKTIENGESELLSCHAFT (DE) 2003-05-01 WO disclosed
US-6506898-B1 Halogen-free, purity; curing agents CYTEC TECHNOLOGY CORP. 2003-01-14 US disclosed
WO-2000027829-A1 PREPARATION OF TRIS-SUBSTITUTED ALKOXYCARBONYLAMINO-1,3,5-TRIAZINE COMPOUNDS CYTEC TECHNOLOGY CORP. (US) 2000-05-18 WO disclosed
US-6063922-A Carbamate functional 1,3,5-triazines CYTEC TECHNOLOGY CORP. (US) 2000-05-16 US disclosed
EP-0976739-A2 A Process for the preparation of 1,3,5-triazine carbamates, at least biscarbimate functional 1,3,5-triazines as well as use of 1,3,5-triazine carbamates CYTEC TECHNOLOGY CORP. (US) 2000-02-02 EP disclosed
US-5792866-A Process for the preparation of 1,3,5-triazine carbamates from amino 1,3,5-triazines and organic carbonates CYTEC TECHNOLOGY CORPORATION (US) 1998-08-11 US disclosed
EP-0649842-B1 Process for preparing derivatives of (halo)amino compounds by carbonylation CYTEC TECH CORP (US) 1998-06-03 EP disclosed
US-5705641-A Process for the preparation of 1,3,5-triazine carbamates from amino-1,3,5-triazines and organic carbonates CYTEC TECHNOLOGY CORP. (US) 1998-01-06 US disclosed
US-5593735-A Aminoresin based coatings containing 1,3,5-triazine tris-carbamate co-crosslinkers CYTEC TECHNOLOGY CORP. (US) 1997-01-14 US disclosed
JP-H07188194-A PREPARATION OF (HALO)AMINO-1,3,5-TRIAZINE DERIVATIVE BY CARBONYLATION CYTEC TECHNOL CORP 1995-07-25 JP disclosed
EP-0649842-A1 Process for preparing derivatives of (halo)amino compounds by carbonylation CYTEC TECHNOLOGY CORP. (US) 1995-04-26 EP disclosed
EP-0624577-A1 Process for the preparation of 1,3,5-triazine carbamates, at least biscarbamate functional 1,3,5-triazines and their use as crosslinkers CYTEC TECHNOLOGY CORP. (US) 1994-11-17 EP disclosed