Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.42 |
| ▸ | CLK1 | P49759 | 5/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840473 | 0.90 | KDM4E (0.57) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7848955 | 0.83 | ALDH1A1 (0.75) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7848393 | 0.83 | ALDH1A1 (0.75) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7848264 | 0.82 | ALDH1A1 (0.72) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7839983 | 0.72 | DYRK1A (0.49) | KMT2AMEN1NPC1RAB9APIM1 | |
| SCHEMBL7840041 | 0.71 | ALDH1A1 (0.57) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL5551397 | 0.70 | GAA (0.43) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL14344321 | 0.70 | GAA (0.43) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL28902601 | 0.70 | KMT2A (0.50) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL14080301 | 0.68 | KMT2A (0.46) | KMT2AMEN1NPC1RAB9APIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | claimed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | claimed |
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | disclosed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | disclosed |