Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848393 | 1.00 | ALDH1A1 (0.75) | ALDH1A1KDM4ENFKB1NFKB2RELA | |
| SCHEMBL7848264 | 0.83 | ALDH1A1 (0.72) | ALDH1A1KDM4ECYP1A2MAPTLMNA | |
| SCHEMBL7850504 | 0.83 | KDM4E (0.72) | ALDH1A1KDM4ECYP1A2MAPTPIM1 | |
| SCHEMBL19184514 | 0.75 | CYP1A2 (0.47) | ALDH1A1KDM4ENFKB1NFKB2RELA | |
| SCHEMBL7840473 | 0.72 | KDM4E (0.57) | ALDH1A1KDM4ECYP1A2MAPTPIM1 | |
| SCHEMBL7840041 | 0.72 | ALDH1A1 (0.57) | ALDH1A1KDM4ECYP1A2MAPTLMNA | |
| SCHEMBL27801861 | 0.68 | NFKB1 (0.42) | ALDH1A1KDM4ENFKB1NFKB2RELA | |
| SCHEMBL5548130 | 0.67 | NFKB1 (0.44) | ALDH1A1KDM4ENFKB1NFKB2RELA | |
| SCHEMBL14344365 | 0.67 | NFKB1 (0.44) | ALDH1A1KDM4ENFKB1NFKB2RELA | |
| SCHEMBL9047452 | 0.65 | CYP1A2 (0.50) | ALDH1A1NFKB1NFKB2RELACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | claimed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | claimed |
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | disclosed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | disclosed |