Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.35 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.35 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.35 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.35 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733560 | 0.91 | TRPV1 (0.41) | TRPV1NPC1RAB9ACNR1CNR2 | |
| SCHEMBL7732431 | 0.85 | TRPV1 (0.41) | TRPV1NPC1RAB9ACNR1CNR2 | |
| SCHEMBL7732373 | 0.81 | TRPV1 (0.50) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL7732103 | 0.78 | RAB9A (0.53) | TRPV1KDRNPC1RAB9AKDM4E | |
| Trifluoroacetic Acid SCHEMBL7735917 | 0.77 | RAB9A (0.48) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL7735550 | 0.76 | TRPV1 (0.52) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL7731720 | 0.76 | TRPV1 (0.41) | TRPV1NPC1RAB9AKDM4ECNR1 | |
| SCHEMBL7733996 | 0.75 | NPC1 (0.50) | TRPV1KDRNPC1RAB9AKDM4E | |
| SCHEMBL7734004 | 0.74 | RAB9A (0.42) | KDRNPC1RAB9AKDM4EBACE1 | |
| SCHEMBL7734013 | 0.73 | NPC1 (0.45) | TRPV1KDRNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |