Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.42 |
| ▸ | NPC1 | O15118 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732052 | 0.92 | RAB9A (0.43) | RAB9ANPC1KDM4ECASP3SENP7 | |
| SCHEMBL7732373 | 0.88 | TRPV1 (0.50) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL7732103 | 0.81 | RAB9A (0.53) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL7731720 | 0.80 | TRPV1 (0.41) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL7733560 | 0.80 | TRPV1 (0.41) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7735917 | 0.78 | RAB9A (0.48) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL7732431 | 0.78 | TRPV1 (0.41) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7733996 | 0.76 | NPC1 (0.50) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL7730721 | 0.75 | LTA4H (0.40) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7850751 | 0.74 | TRPV1 (0.44) | RAB9ANPC1KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |