Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 8/20 | 0.49 |
| ▸ | EDNRB | P24530 | 6/20 | 0.49 |
| ▸ | DHPS | P49366 | 9/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426889 | 0.87 | EDNRA (0.49) | EDNRAEDNRBDHPS | |
| SCHEMBL7851591 | 0.81 | DHPS (0.56) | EDNRAEDNRBDHPS | |
| SCHEMBL8329894 | 0.77 | EDNRA (0.60) | EDNRAEDNRB | |
| SCHEMBL4426886 | 0.76 | EDNRA (0.38) | EDNRAEDNRBDHPSSCN9AKDR | |
| SCHEMBL8354976 | 0.75 | EDNRA (0.67) | EDNRAEDNRBSCN9A | |
| Benzamide SCHEMBL7592195 | 0.74 | EDNRA (0.69) | EDNRAEDNRBDHPS | |
| SCHEMBL9092381 | 0.73 | EDNRA (0.58) | EDNRAEDNRB | |
| SCHEMBL14380740 | 0.73 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL8321011 | 0.73 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL6972287 | 0.73 | DHPS (0.42) | EDNRAEDNRBDHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713875-B1 | Sulfonamides | HOFFMANN LA ROCHE (CH) | 2001-03-21 | — | — | EP | claimed |