Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337912 | 0.73 | RAB9A (0.71) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7124063 | 0.72 | SMN1; SMN2 (0.68) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3159167 | 0.70 | ALDH1A1 (0.71) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4875267 | 0.70 | ALDH1A1 (0.79) | MAPTSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL11026303 | 0.68 | ALDH1A1 (0.65) | MAPTSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL10418997 | 0.68 | HTT (0.63) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL15565060 | 0.68 | ALDH1A1 (0.47) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28486691 | 0.68 | RAB9A (0.52) | MAPTRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5751576 | 0.68 | MAPT (0.52) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11671841 | 0.68 | ALPL (0.70) | MAPTSMN1; SMN2KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710658-B1 | 5-(Aryloxymethyl)oxazolines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-04 | — | — | EP | disclosed |
| CN-1051545-C | New 5-(aryloxymethyl) oxazolines, a process for the preparation thereof and pharmaceutical compositions containing them | ADIR (FR) | 2000-04-19 | — | — | CN | disclosed |
| US-5686477-A | HYPOTENSIVE AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-11 | — | — | US | disclosed |
| CN-1129697-A | New 5-(aryloxymethyl) oxazolines, a process for the preparation thereof and pharmaceutical compositions containing them | ADIR (FR) | 1996-08-28 | — | — | CN | disclosed |
| EP-0710658-A1 | 5-(Aryloxymethyl)oxazolines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-08 | — | — | EP | disclosed |