Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852926 | 0.86 | GAA (0.38) | L3MBTL1POLBPTGS2SLC13A5MTNR1A | |
| SCHEMBL8881289 | 0.85 | ATR (0.46) | HDAC6L3MBTL1POLBPTGS2FFAR1 | |
| SCHEMBL16611199 | 0.80 | ALDH1A1 (0.41) | L3MBTL1POLBNPSR1SLC13A5MTNR1A | |
| SCHEMBL7499858 | 0.75 | SLC13A5 (0.63) | HDAC6L3MBTL1POLBPTGS2SLC13A5 | |
| SCHEMBL7849614 | 0.75 | PDE4D (0.38) | L3MBTL1FFAR4 | |
| SCHEMBL8496285 | 0.73 | AR (0.39) | L3MBTL1POLBSLC13A5MTNR1ALMNA | |
| SCHEMBL7851013 | 0.73 | SLC13A5 (0.39) | L3MBTL1POLBPTGS2SLC13A5GAA | |
| SCHEMBL8885211 | 0.71 | ATR (0.48) | SLC13A5GAA | |
| SCHEMBL30885486 | 0.71 | ATR (0.48) | SLC13A5MTNR1A | |
| SCHEMBL7852447 | 0.70 | PTGS2 (0.35) | POLBPTGS2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| EP-0717743-A1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-06-26 | — | — | EP | disclosed |