Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13120792 | 0.81 | L3MBTL1 (0.40) | ARL3MBTL1MAPTF2HSD17B10 | |
| SCHEMBL13120797 | 0.81 | L3MBTL1 (0.40) | ARL3MBTL1MAPTF2HSD17B10 | |
| SCHEMBL13120795 | 0.81 | HTT (0.43) | L3MBTL1MAPTF2HSD17B10KDM4E | |
| SCHEMBL29958183 | 0.79 | L3MBTL1 (0.38) | ARL3MBTL1MAPTF2HSD17B10 | |
| SCHEMBL7852926 | 0.75 | GAA (0.38) | L3MBTL1MAPTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL27733088 | 0.74 | KDM4E (0.49) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7852449 | 0.73 | HDAC6 (0.42) | L3MBTL1MTNR1ALMNASLC13A5POLB | |
| SCHEMBL12666586 | 0.73 | CYP2C19 (0.50) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16611199 | 0.72 | ALDH1A1 (0.41) | L3MBTL1MAPTALDH1A1HPGDMTNR1A | |
| SCHEMBL8885211 | 0.72 | ATR (0.48) | HSD17B10SLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| US-7812038-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2010-10-12 | — | — | US | disclosed |
| US-7812038-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2010-10-12 | — | — | US | disclosed |