Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | TERT | O14746 | 6/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843357 | 0.90 | MAOB (0.47) | DRD1MAOBMAOA | |
| SCHEMBL7851641 | 0.82 | MAOB (0.38) | NPC1ALDH1A1RAB9AMAOBTERT | |
| SCHEMBL7850608 | 0.72 | PTGES (0.35) | NPC1ALDH1A1RAB9AMAOBTERT | |
| SCHEMBL7849461 | 0.71 | MAOB (0.48) | MAOBMAOA | |
| SCHEMBL8087595 | 0.71 | MAOB (0.45) | DRD1MAOBHDAC1HDAC6HDAC5 | |
| SCHEMBL8131549 | 0.65 | HDAC1 (0.47) | NPC1ALDH1A1RAB9AMAOBTERT | |
| SCHEMBL24933815 | 0.65 | NPC1 (0.43) | NPC1ALDH1A1RAB9AMAOBTERT | |
| SCHEMBL30240772 | 0.65 | NPC1 (0.43) | NPC1ALDH1A1RAB9AMAOBTERT | |
| SCHEMBL8489930 | 0.65 | MAOB (0.48) | NPC1RAB9AMAOBMAOA | |
| SCHEMBL8137593 | 0.64 | CHRM5 (0.41) | NPC1ALDH1A1RAB9AMAOBTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066267-A1 | SUBSTITUTED PHENYL URACILS | Bayer Aktiengesellschaft (DE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999028302-A1 | SUBSTITUTED PHENYL URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-06-10 | — | — | WO | disclosed |