Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 5/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851641 | 0.90 | MAOB (0.38) | MAOBLMNASMN1; SMN2NPSR1PTGES | |
| SCHEMBL7851719 | 0.85 | MAOB (0.52) | MAOBARNPSR1MAOA | |
| SCHEMBL7843357 | 0.81 | MAOB (0.47) | MAOBARMAOA | |
| SCHEMBL7850608 | 0.79 | PTGES (0.35) | MAOBLMNASMN1; SMN2NPSR1PTGES | |
| SCHEMBL8087595 | 0.75 | MAOB (0.45) | MAOBMAOA | |
| SCHEMBL7841395 | 0.74 | MAOB (0.44) | MAOBARLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7612058 | 0.72 | BCAT2 (0.42) | MAOBARLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7854098 | 0.71 | NPC1 (0.40) | MAOBMAOA | |
| SCHEMBL7610613 | 0.71 | MAOB (0.41) | MAOBARPTGESMAOATLR4 | |
| SCHEMBL2964633 | 0.69 | MAOB (0.52) | MAOBLMNASMN1; SMN2NPSR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066267-A1 | SUBSTITUTED PHENYL URACILS | Bayer Aktiengesellschaft (DE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999028302-A1 | SUBSTITUTED PHENYL URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-06-10 | — | — | WO | disclosed |