Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 6/20 | 0.55 |
| ▸ | PLAU | P00749 | 10/20 | 0.55 |
| ▸ | PLG | P00747 | 6/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.55 |
| ▸ | PLAT | P00750 | 5/20 | 0.55 |
| ▸ | KLK1 | P06870 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340137 | 0.92 | F2 (0.65) | NPC1RAB9AMAPTMAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL7853602 | 0.84 | PLAU (0.70) | NPC1RAB9AF2PLAUPLG | |
| Trifluoroacetic Acid SCHEMBL7854660 | 0.83 | NPC1 (0.59) | NPC1RAB9AMAOB | |
| Trifluoroacetic Acid SCHEMBL7338129 | 0.81 | PLAU (0.67) | F2PLAUPLGKLKB1PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7335035 | 0.80 | PLAU (0.63) | F2PLAUPLGKLKB1PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7853575 | 0.80 | MAOB (0.58) | NPC1RAB9AMAOBF2PLAU | |
| Trifluoroacetic Acid SCHEMBL7359134 | 0.80 | PLAU (0.66) | F2PLAUPLGKLKB1PRSS1 | |
| SCHEMBL7854268 | 0.79 | NPC1 (0.46) | NPC1RAB9AMAPTMAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL7335882 | 0.79 | PLAU (0.74) | F2PLAUPLGKLKB1PRSS1 | |
| SCHEMBL6632654 | 0.79 | NPC1 (0.75) | NPC1RAB9AMAPTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | STEELE ANDREW W (US) | 2001-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | SERPINE1, PLAU, SERPINB1 | NPC1 2478/4885RAB9A 2845/4885MAPT 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.