Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 8/20 | 0.54 |
| ▸ | PLG | P00747 | 5/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.54 |
| ▸ | F2 | P00734 | 4/20 | 0.54 |
| ▸ | PLAT | P00750 | 4/20 | 0.54 |
| ▸ | KLK1 | P06870 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7854660 | 0.93 | NPC1 (0.59) | MAOBMAP4K4CLK2DYRK1ACLK4 | |
| SCHEMBL7337800 | 0.92 | MAP4K4 (0.66) | MAOBMAP4K4CLK2DYRK1ASRPK1 | |
| SCHEMBL7341317 | 0.85 | MAOB (0.65) | MAOBMAP4K4CLK2DYRK1ACLK4 | |
| Trifluoroacetic Acid SCHEMBL7853602 | 0.81 | PLAU (0.70) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7854264 | 0.80 | NPC1 (0.58) | MAOBPLAUPLGKLKB1PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7338129 | 0.80 | PLAU (0.67) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7359134 | 0.79 | PLAU (0.66) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7344122 | 0.77 | PLAU (0.84) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7335035 | 0.77 | PLAU (0.63) | PLAUPLGKLKB1PRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7855921 | 0.76 | PABPC1 (0.60) | PLAUPLGKLKB1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | STEELE ANDREW W (US) | 2001-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | SERPINE1, PLAU, SERPINB1 | MAOB 666/4885MAP4K4 871/4885CLK2 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.