Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10958629 | 0.86 | ELANE (0.50) | L3MBTL1ELANEKDM4ETSHRTHRA | |
| SCHEMBL5608091 | 0.81 | TDP1 (0.52) | NPSR1MAPTELANEKDM4EMEN1 | |
| SCHEMBL28008661 | 0.80 | ELANE (0.45) | L3MBTL1NPSR1MAPTELANEKDM4E | |
| SCHEMBL453104 | 0.80 | ELANE (0.46) | L3MBTL1MAPTELANEHSD17B10 | |
| SCHEMBL15867625 | 0.80 | ELANE (0.61) | L3MBTL1NPSR1MAPTELANEGABRA1 | |
| SCHEMBL7182176 | 0.78 | L3MBTL1 (0.43) | L3MBTL1NPSR1MAPTELANETSHR | |
| SCHEMBL47951 | 0.77 | L3MBTL1 (0.48) | L3MBTL1NPSR1MAPTKDM4ETSHR | |
| Benzene SCHEMBL28173619 | 0.75 | PTGS2 (0.58) | L3MBTL1NPSR1MAPTELANEKDM4E | |
| SCHEMBL7064536 | 0.75 | L3MBTL1 (0.50) | L3MBTL1NPSR1MAPTKDM4ETSHR | |
| SCHEMBL29587376 | 0.75 | L3MBTL1 (0.50) | L3MBTL1NPSR1MAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288046-B1 | ACETYLATED ALPHA-LINKED ACIDIC DIPEPTIDASE/N-/ INHIBITORS; CARBOXYALKYLPHOSPHATES; PROSTATE DISORDERS; GLUTAMATE ABNORMALITIES; NERVOUS SYSTEM DISORDERS | GUILFORD PHARMACEUTICALS INC. | 2001-09-11 | — | — | US | disclosed |
| WO-1998047906-A1 | PHOSPHONIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1998-10-29 | — | — | WO | disclosed |