SCHEMBL7064536

SCHEMBL7064536

CCc1ccccc1OC(=O)C(=O)Oc1ccccc1CC

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.50
MAPT P10636 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
TSHR P16473 2/20 0.44
HSD17B10 Q99714 1/20 0.44
HPGD P15428 1/20 0.43
ATM Q13315 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8755535 0.90 L3MBTL1 (0.46) L3MBTL1MAPTNPSR1THRATHRB
SCHEMBL7064539 0.90 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1THRATHRB
SCHEMBL147468 0.88 ELANE (0.47) L3MBTL1MAPTNPSR1THRATHRB
SCHEMBL10927772 0.88 L3MBTL1 (0.44) L3MBTL1MAPTNPSR1THRATHRB
SCHEMBL21551503 0.88 L3MBTL1 (0.44) L3MBTL1MAPTNPSR1THRATHRB
SCHEMBL29587376 0.87 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1THRATHRB
SCHEMBL47950 0.87 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1THRATHRB
SCHEMBL27581710 0.87 L3MBTL1 (0.43) L3MBTL1MAPTNPSR1THRATHRB
SCHEMBL7065312 0.86 THRA (0.53) NPSR1THRATHRB
SCHEMBL28825873 0.85 THRA (0.42) L3MBTL1MAPTNPSR1THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9174918-B2 Process for preparing diaryl oxalate UBE INDUSTRIES, LTD. (JP) 2015-11-03 US disclosed
US-20120296063-A1 PROCESS FOR PREPARING DIARYL OXALATE UBE CORPORATION (JP) 2012-11-22 US disclosed
CN-102473775-A Sealing material for solar cell SUMITOMO CHEMICAL CO 2012-05-23 CN disclosed
EP-1013633-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2003-05-28 EP disclosed
EP-0795539-B1 Process for producing a diaryl carbonate UBE INDUSTRIES (JP) 2001-10-31 EP disclosed
EP-0814074-B1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES (JP) 2001-03-28 EP disclosed
EP-1013633-A1 Process for producing a diaryl carbonate Ube Industries, Ltd. (JP) 2000-06-28 EP disclosed
US-6018072-A SUBJECTING AN ALKYLARYL OXALATE TO A DISPROPORTIONATION REACTION IN THE PRESENCE OF A DISPROPORTIONATION CATALYST TO PRODUCE A DIARYL OXALATE WHILE REMOVING A DIALKYL OXALATE BY-PRODUCT UBE INDUSTRIES, LTD. (JP) 2000-01-25 US disclosed
US-5811573-A Process for producing a diaryl carnonate UBE INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed
US-5731453-A Process for producing a diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
EP-0814074-A1 PROCESS FOR PREPARING DIARYL ESTERS OF OXALIC ACID UBE INDUSTRIES, LTD. (JP) 1997-12-29 EP disclosed
EP-0795539-A1 Process for producing a diaryl carbonate UBE INDUSTRIES LIMITED (JP) 1997-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120296063-A1 PROCESS FOR PREPARING DIARYL OXALATE TH, CYP2E1, ADH1A L3MBTL1 3408/4885MAPT 1977/4885NPSR1 1416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.