Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860976 | 1.00 | MAPT (0.33) | MAPTGAAALDH1A1LMNAGUSB | |
| SCHEMBL7864405 | 0.89 | MAPT (0.31) | MAPTGAAALDH1A1 | |
| SCHEMBL7860988 | 0.86 | MMP9 (0.32) | MAPTGAAALDH1A1 | |
| SCHEMBL7861006 | 0.85 | MAPT (0.38) | MAPTGAAALDH1A1LMNAGUSB | |
| SCHEMBL7864329 | 0.84 | ADORA2B (0.35) | — | |
| SCHEMBL7860961 | 0.80 | MMP2 (0.34) | MAPTGAAALDH1A1LMNA | |
| SCHEMBL7861108 | 0.79 | — | — | |
| SCHEMBL7861417 | 0.79 | — | — | |
| SCHEMBL7861448 | 0.77 | TP53 (0.31) | MAPT | |
| SCHEMBL7864335 | 0.77 | TP53 (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812835-B1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO CO (JP) | 2001-05-23 | — | — | EP | claimed |