Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861922 | 0.85 | MEN1 (0.48) | ATMMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL7862038 | 0.84 | MEN1 (0.52) | ATMMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL3736148 | 0.81 | ATM (0.54) | ATMMEN1KMT2ACA1CA2 | |
| SCHEMBL22468533 | 0.80 | MEN1 (0.66) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL3735186 | 0.78 | CYP3A4 (0.54) | ATMMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL15056984 | 0.78 | KMT2A (0.56) | ATMMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL8476244 | 0.76 | MEN1 (0.54) | ATMMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL2406040 | 0.76 | ITGB3 (0.61) | ATMMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL16468538 | 0.76 | ATM (0.64) | ATMMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL25754099 | 0.76 | ALDH1A1 (0.61) | ATMMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121366-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-1999051613-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 1999-10-14 | — | — | WO | disclosed |