Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355188 | 0.82 | TAAR1 (0.40) | TAAR1MAOBCYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL6431657 | 0.79 | TAAR1 (0.52) | TAAR1MAOBCYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL7717778 | 0.76 | LAP3 (0.39) | CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL5586462 | 0.75 | SRC (0.55) | CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL12569396 | 0.75 | TAAR1 (0.57) | TAAR1MAOBCYP2C19SMN1; SMN2NOS3 | |
| SCHEMBL29038811 | 0.73 | RAB9A (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL23235728 | 0.72 | PPARA (0.41) | CYP2C19SMN1; SMN2 | |
| SCHEMBL15996603 | 0.71 | SMN1; SMN2 (0.51) | CYP2C19SMN1; SMN2CYP1A2KDM4EALDH1A1 | |
| SCHEMBL5179183 | 0.70 | CA2 (0.54) | TAAR1MAOBCYP1A2CYP2A6 | |
| SCHEMBL8732769 | 0.69 | PTPN1 (0.60) | TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000075167-A9 | PHOSPHORYLATION ASSAYS | LJL BIOSYSTEMS INC (US) | 2001-06-28 | — | — | WO | claimed |