Asparagine

SCHEMBL7855451

C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.O=C(O)[C@@H]1[C@@H](c2ccc3ccccc3c2)CCN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	6/20	0.36

▸	TACR1	P25103	1/20	0.35

▸	FABP7	O15540	1/20	0.33

▸	FABP5	Q01469	1/20	0.33

▸	PIN1	Q13526	1/20	0.32

▸	SLC6A4	P31645	2/20	0.32

▸	SLC6A3	Q01959	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Asparagine SCHEMBL2902137	0.96	MC4R (0.35)	MC4RTACR1FABP7FABP5PIN1
SCHEMBL2906513	0.88	FABP5 (0.42)	FABP7FABP5SLC6A4SLC6A3
SCHEMBL1675974	0.77	FABP5 (0.50)	MC4RTACR1FABP7FABP5SLC6A4
SCHEMBL1675971	0.77	FABP5 (0.50)	MC4RTACR1FABP7FABP5SLC6A4
SCHEMBL31582094	0.74	FABP5 (0.43)	FABP7FABP5
SCHEMBL31524267	0.74	FABP5 (0.43)	FABP7FABP5
SCHEMBL4040012	0.70	FABP5 (0.45)	FABP7FABP5
SCHEMBL3423135	0.70	FABP5 (0.47)	FABP7FABP5
SCHEMBL4050272	0.70	FABP5 (0.47)	FABP7FABP5
SCHEMBL30686169	0.70	FABP5 (0.47)	FABP7FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1157040-A1	LOW MOLECULAR WEIGHT PEPTIDE DERIVATIVES AS INHIBITORS OF THE LAMININ/NIDOGEN INTERACTION	Aventis Pharma Deutschland GmbH (DE)	2001-11-28	—	—	EP	disclosed
WO-2000052051-A1	LOW MOLECULAR WEIGHT PEPTIDE DERIVATIVES AS INHIBITORS OF THE LAMININ/NIDOGEN INTERACTION	AVENTIS PHARMA DEUTSCHLAND GMBH (DE)	2000-09-08	—	—	WO	disclosed