Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856292 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TAAR1KDM4EL3MBTL1MAPT | |
| SCHEMBL22701023 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTTSHRHTR1A | |
| SCHEMBL28050539 | 0.81 | HTR1A (0.44) | TAAR1L3MBTL1MAPTNPSR1HRH1 | |
| SCHEMBL14151108 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EL3MBTL1MAPTTSHR | |
| SCHEMBL8523471 | 0.79 | HRH1 (0.54) | L3MBTL1TSHRHPGDHRH1HTR1A | |
| SCHEMBL21413931 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EL3MBTL1MAPTTSHR | |
| SCHEMBL1907827 | 0.76 | CA1 (0.52) | ALDH1A1TAAR1L3MBTL1TSHRPOLB | |
| SCHEMBL27397678 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EL3MBTL1MAPTNPSR1 | |
| SCHEMBL11305271 | 0.76 | GAA (0.55) | ALDH1A1MAPTTSHRHPGDDRD2 | |
| SCHEMBL8025735 | 0.75 | HPGD (0.46) | ALDH1A1L3MBTL1MAPTAKR1C3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |