Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251894 | 0.81 | ALDH1A1 (0.54) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL7856293 | 0.81 | ALDH1A1 (0.40) | HTR1ATAAR1HRH1MAPTNPSR1 | |
| SCHEMBL7856292 | 0.81 | ALDH1A1 (0.40) | HTR1ATAAR1HRH1MAPTNPSR1 | |
| SCHEMBL22701023 | 0.78 | ALDH1A1 (0.50) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL8523471 | 0.78 | HRH1 (0.54) | HTR1AHRH1L3MBTL1DRD2 | |
| SCHEMBL4262567 | 0.77 | L3MBTL1 (0.60) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL74512 | 0.76 | PPARD (0.54) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL27984338 | 0.74 | PPARD (0.47) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL2428495 | 0.74 | HTR1A (0.49) | HTR1AADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL1907827 | 0.74 | CA1 (0.52) | TAAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418388-A | Preparation method for flame retardant of 2,2-bis [3,5-dibromo-4-(2,3-dibromo-2-methyl propoxy) phenyl] propane | QIAN LIJUN | 2016-03-23 | — | — | CN | disclosed |