Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | CHRND | Q07001 | 10/20 | 0.54 |
| ▸ | CHRNA1 | P02708 | 6/20 | 0.54 |
| ▸ | CHRNG | P07510 | 6/20 | 0.54 |
| ▸ | CHRNB1 | P11230 | 6/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859128 | 0.94 | CALCRL (0.51) | MMP2MMP9MMP8CHRNDCHRNA1 | |
| SCHEMBL8163585 | 0.88 | MMP2 (0.49) | MMP2MMP9MMP8CHRNDCHRNA1 | |
| SCHEMBL7850349 | 0.86 | OPRD1 (0.50) | MMP2MMP9MMP8CHRNDCHRNA1 | |
| SCHEMBL7857865 | 0.84 | FCER2 (0.60) | MMP2MMP9MMP8CHRNDCHRNA1 | |
| SCHEMBL7855910 | 0.83 | FCER2 (0.47) | MMP2MMP9MMP8CHRNDCHRNA1 | |
| Hydrochloric Acid SCHEMBL8617569 | 0.81 | NPY4R (0.59) | MMP2MMP9MMP8CHRNDCHRNA1 | |
| SCHEMBL7857956 | 0.81 | HDAC8 (0.57) | MMP2MMP9MMP8OPRD1 | |
| SCHEMBL7857952 | 0.81 | HDAC8 (0.57) | MMP2MMP9MMP8OPRD1 | |
| Trifluoroacetic Acid SCHEMBL7857126 | 0.81 | OPRD1 (0.47) | MMP2MMP9MMP8CHRNDCHRNA1 | |
| SCHEMBL8365152 | 0.80 | HDAC8 (0.53) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |