Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 5/20 | 0.51 |
| ▸ | CHRNG | P07510 | 5/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 5/20 | 0.51 |
| ▸ | CHRND | Q07001 | 5/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.49 |
| ▸ | FCER2 | P06734 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857087 | 0.94 | MMP2 (0.59) | CALCRLMMP2MMP9MMP8CHRNA1 | |
| SCHEMBL7857865 | 0.90 | FCER2 (0.60) | MMP2MMP9MMP8CHRNA1CHRNG | |
| SCHEMBL7850349 | 0.88 | OPRD1 (0.50) | MMP2MMP9MMP8CHRNA1CHRNG | |
| SCHEMBL8163585 | 0.88 | MMP2 (0.49) | CALCRLMMP2MMP9MMP8CHRNA1 | |
| Trifluoroacetic Acid SCHEMBL7860784 | 0.85 | FCER2 (0.57) | MMP2MMP9MMP8CHRNA1CHRNG | |
| Trifluoroacetic Acid SCHEMBL7857126 | 0.84 | OPRD1 (0.47) | MMP2MMP9MMP8CHRNA1CHRNG | |
| SCHEMBL7857984 | 0.84 | GRIA1 (0.55) | CALCRLMMP2MMP8CHRNA1CHRNG | |
| SCHEMBL29616642 | 0.83 | MME (0.57) | MMP2FCER2 | |
| SCHEMBL7855910 | 0.82 | FCER2 (0.47) | MMP2MMP9MMP8CHRNA1CHRNG | |
| SCHEMBL7857825 | 0.81 | CALCRL (0.46) | CALCRLMMP2MMP9MMP8CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |