Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | GLS | O94925 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437304 | 0.76 | AOC3 (0.36) | AOC3S1PR3XPO1SMN1; SMN2 | |
| SCHEMBL5949849 | 0.76 | AOC3 (0.36) | AOC3S1PR3XPO1SMN1; SMN2 | |
| SCHEMBL5949847 | 0.76 | AOC3 (0.36) | AOC3S1PR3XPO1SMN1; SMN2 | |
| SCHEMBL7069969 | 0.74 | ADRB3 (0.35) | AOC3S1PR3KDM4EIDO1CTSL | |
| SCHEMBL5950226 | 0.74 | AOC3 (0.35) | AOC3S1PR3KDM4EXPO1SMN1; SMN2 | |
| SCHEMBL9267480 | 0.74 | AOC3 (0.36) | AOC3S1PR3KDM4EIDO1XPO1 | |
| SCHEMBL9063602 | 0.74 | AOC3 (0.43) | AOC3IDO1 | |
| SCHEMBL7392343 | 0.73 | AOC3 (0.46) | AOC3IDO1CA2 | |
| SCHEMBL7151078 | 0.73 | AOC3 (0.46) | AOC3IDO1CA2 | |
| SCHEMBL7977761 | 0.72 | AOC3 (0.35) | AOC3S1PR3XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043953-A1 | NAPHTHALENESULPHONIC OR CARBOXYLIC ACIDS AND THEIR USE AS ATYPICAL BETA-ADRENOCEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |