Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785549 | 1.00 | MAPT (0.41) | MAPTCRBNPOLBRORCAKR1C3 | |
| SCHEMBL803567 | 0.88 | MAPT (0.41) | MAPTCRBNPOLBPARP1PARP2 | |
| SCHEMBL2816152 | 0.84 | CRBN (0.42) | MAPTCRBNPOLBRORCAKR1C3 | |
| SCHEMBL785723 | 0.84 | CRBN (0.42) | MAPTCRBNPOLBRORCAKR1C3 | |
| SCHEMBL785795 | 0.84 | CRBN (0.42) | MAPTCRBNPOLBRORCAKR1C3 | |
| SCHEMBL484302 | 0.83 | CRBN (0.42) | MAPTCRBNPOLBRORCAKR1C3 | |
| SCHEMBL785044 | 0.83 | CRBN (0.42) | MAPTCRBNPOLBRORCAKR1C3 | |
| SCHEMBL2821894 | 0.83 | MAPT (0.46) | MAPTCRBNPOLBPARP1HTR2A | |
| SCHEMBL2816182 | 0.83 | MAPT (0.46) | MAPTCRBNPOLBPARP1HTR2A | |
| SCHEMBL877902 | 0.78 | MTNR1B (0.40) | MAPTCRBNPOLBPARP1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | MAPT 3149/4885CRBN 3728/4885POLB 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.