SCHEMBL7857549

SCHEMBL7857549

NC1=Nc2[nH]cnc2C(=O)[N]1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
PNP P00491 2/20 0.30
ABL1 P00519 1/20 0.30
RIN1 Q13671 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1072291 0.65 IDO1 (0.36)
SCHEMBL13735762 0.56 ALDH1A1 (0.65) ALDH1A1POLBRXFP1
SCHEMBL2044444 0.54 PNP (0.37) ALDH1A1PNPABL1RIN1
SCHEMBL13946583 0.53 KDM4E (0.54) ALDH1A1
SCHEMBL13863 0.53
SCHEMBL4455591 0.53
SCHEMBL21169645 0.53
SCHEMBL4458196 0.53
Hydrochloric Acid SCHEMBL11693353 0.51
SCHEMBL1094924 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845476-B1 Synthetic catalytic oligonucleotides EUROPAEISCHES LAB FUER (DE) 2001-03-14 EP disclosed
EP-1061085-A2 Synthetic catalytic oligonucleotides EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (EMBL) (DE) 2000-12-20 EP disclosed
EP-0519463-B1 Synthetic, catalytic oligonucleotides EUROP LAB MOLEKULARBIOLOG (DE) 1998-10-21 EP disclosed
EP-0845476-A2 Synthetic catalytic oligonucleotides EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (EMBL) (DE) 1998-06-03 EP disclosed
US-5334711-A To cleave a nucleic acid target sequence; double-stranded; increased stability; reduced protein interaction; viricides; AIDS EUROPAISCHES LABORATORIUM FUR MOLEKULARBIOLOGIE (EMBL) (DE) 1994-08-02 US disclosed
EP-0519463-A1 Synthetic, catalytic oligonucleotides EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (EMBL) (DE) 1992-12-23 EP disclosed