Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859907 | 0.88 | PSEN1 (0.39) | TDP1KMT2AMEN1MAOBCA12 | |
| SCHEMBL7860674 | 0.88 | TDP1 (0.45) | TDP1ATMCCR5MAPTNPC1 | |
| SCHEMBL9522440 | 0.87 | TDP1 (0.38) | TDP1MAOBATMCCR5MAPT | |
| SCHEMBL7805407 | 0.86 | ALDH1A1 (0.41) | TDP1MAOBATMCCR5MAPT | |
| SCHEMBL6397203 | 0.85 | TDP1 (0.46) | TDP1MAOBATMMAOAMAPT | |
| SCHEMBL9519224 | 0.85 | ALDH1A1 (0.37) | TDP1MAOBATMCCR5MAPT | |
| SCHEMBL9795094 | 0.84 | ALDH1A1 (0.37) | TDP1MAOBATMCCR5MAPT | |
| SCHEMBL9520276 | 0.84 | ALDH1A1 (0.37) | TDP1MAOBATMCCR5CA12 | |
| SCHEMBL9519220 | 0.84 | ALDH1A1 (0.37) | TDP1MAOBATMCCR5CA12 | |
| SCHEMBL7859859 | 0.83 | CCR5 (0.40) | TDP1KMT2AMEN1ATMCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |